Australian breast cancer rates decline with decreased HRT use
1 June 2008
A significant decline in breast cancer rates amongst Australian women aged over 50 years has been linked to a recent dramatic decrease in the use of hormone replacement therapy (HRT), according to new research by Cancer Council NSW.
The research, published in Medical Journal Australia, found that the use of HRT in Australia dropped by 40 per cent from 2001 to 2003 following the US Women's Health Initiative study, which highlighted HRT's adverse effects. During the same period, there was a significant seven per cent drop in breast cancer rates among women aged 50 and over, which is equivalent to 600 fewer cases of breast cancer among Australian women.
Dr Karen Canfell, lead author of this breakthrough Australian research said, “This research replicates recent findings from the US, which also showed a substantial decline in breast cancer attributed largely to declining use of HRT”.
Associate Professor Emily Banks at Australian National University, co-author of the study added, “To increase the reliability of our study, we ruled out breast cancer screening trends and other factors, including use of medication, as major contributors to this fall in breast cancer incidence in women 50 years and over.”
Dr Andrew Penman, CEO at The Cancer Council NSW believes these findings are positive, indicating that the decision of women and their health professionals to curtail the use of HRT has resulted in a substantial drop in breast cancer at population level.
For more information:
Media release
Study summary and FAQs
Research report