Clinical practice guidelines for surveillance colonoscopy
Colorectal cancer (CRC) is the second most common internal malignancy affecting Australians. Age-standardised incidence and mortality rates are falling, yet CRC still kills more Australians than any other cancer except for lung cancer despite the fact that CRC biology offers a window of opportunity for prevention and cure.
The adenoma-cancer sequence means that appropriately timed colonoscopy could dramatically reduce both CRC incidence and mortality by detecting and completely removing conventional and serrated adenomas, from which the majority of CRC arises. To maximise this potential benefit, colonoscopy must be performed to a very high standard at appropriate intervals.